Ukukhula okumangalisayo kwemishini yezokwelapha, izimboni ze-biomedical kanye nokunakekelwa kwezempilo kule minyaka eyi-15 edlule kuyaqhubeka ngaphandle kokuphazanyiswa njengoba izinto ezifana nama-fluoropolymers zihlangabezana nesidingo esikhulayo semikhiqizo nezinqubo ezintsha.
Ngokuvamile, ama-fluoropolymers ashintsha kancane kancane esikhundleni samanye amapulasitiki ezinhlelweni zezokwelapha ngenxa yekhono lawo lokuhlangabezana nezidingo zomzimba kanye ne-biocompatibility yezidakamizwa nemishini yesizukulwane esilandelayo.Ama-fluoropolymers ahlangabezana nesethi ehlukile yemibandela yokusebenza ezinhlelweni ezinjalo.Lokhu kufaka phakathi i-biocompatibility, i-lubricity, inzalo, ukungangenisi kwamakhemikhali, ububanzi bokusetshenziswa kwezinga lokushisa, ukubophezela okuphansi kokucubungula imishini, ukuhlanzeka okuphezulu nokukhipha okuphansi, izakhiwo ze-dielectric, kanye nesitifiketi se-USP Class VI.
Umndeni wama-fluoropolymer atholakalayo ahlangabezana nezidingo ezingenhla uhlanganisa amabanga e-PTFE, FEP, PFA kanye ne-PVDF resin avela kubakhiqizi abahlukahlukene benhlaka.I-PTFE(i-polymer) inomlando wokufakelwa osungulwe kahle wokushintshwa kwezicubu ezithambile ngenxa yokuhambisana kwayo kwezinto eziphilayo kanye nokungabi namandla.I-resin kanye nabakhiqizi bomkhiqizo owela phansi bayaqhubeka nokuphendula kuzidingo zokusebenza ezintsha ngokwenza izinguquko ezifanele kukhemistri ye-resin kanye nokucushwa kwendawo yemikhiqizo, ngokulandelanayo.
I-biocompatibility yanoma iyiphi i-polymer iyisidingo esiyinhloko kunoma iyiphi idivayisi yezokwelapha njengama-catheter, imikhumbi ye-bio-containment, amasirinji nama-sutures.I-PTFE, FEP kanye ne-PVDF izinto ezisebenza kahle ezihambisana ne-biocompatible, futhi ukuthambisa kwazo nokumelana namakhemikhali kuzenza zibe izinto ezikhethwayo emikhiqizweni efana namashubhu e-lumen amaningi neminye esetshenziswa ezinqubweni ezihlasela kancane.I-Multi lumen fluoropolymer catheter tubing isibonelo ivumela odokotela abahlinzayo ukuthi benze izinqubo eziningi besebenzisa i-catheter efanayo.
Ama-fluoropolymers, ikakhulukazi i-PTFE(polymer) kanye ne-PVDF asetshenziswa kakhulu kumalwelwesi amancane.Amamembrane, aqukethe izigidigidi zezimbotshana ezinobukhulu obusuka ku-0.01 kuya ku-10 microns asebenza njengezihlungi zezinhlayiya namagciwane oketshezi olubalulekile.I-PTFE ne-PVDF ziphakathi kwama-polymer ambalwa asetshenziselwa ulwelwesi lokuhlunga.Izingxenye ezingaphezulu zolwelwesi lwama-polymers zingashintshwa ukuze zilethe izici ezithile zokuhlunga futhi zingaba yi-hydrophobic (ukuxosha amanzi) kanye ne-oleophobic (uwoyela, i-solvent, i-low surface tension fluid repelling).Ulwelwesi lwe-PVDF lungabuye lulungiswe phezulu lube yi-hydrophilic (ukuthanda amanzi) ukuze kukhishwe izinhlayiya zegciwane lapho kwakhiwa amaprotheni okwelapha kanye namasosha omzimba angama-monoclonal.Ulwelwesi oluvalayo lwe-PVDF lufaneleka kahle kakhulu ekuvinjweni kwengemuva eliphansi (ukuhlaziywa kwe-blot yasentshonalanga), kanye nokuhlaziywa kwe-amino acid nokulandelana kwamaprotheni.
Izinto ezisetshenziswayo, njengamaphampu, amashubhu, okokufakwayo okusetshenziswe ngokuhambisana nemishini yezokwelapha kufanele ihlangabezane nemigomo yokusebenza efanayo kanye nezicaciso.Izesekeli ezithintana ngqo noketshezi zakhiwe ngama-fluoropolymers afana ne-PTFE ne-PVDF.Isibonelo, amaphampu okulinganisa amaphampu afana namaphampu e-diaphragm ayadingeka ukuze kugeleze okunembayo nokuphindaphindayo, ngezinye izikhathi oketshezini olunolaka lwamakhemikhali.Kokubili amashubhu e-PTFE kanye ne-PVDF asetshenziswa ekwakhiweni kwala maphampu ngenxa yalesi sizathu.
I-PVDF, nakuba inomkhawulo ophansi wokusebenzisa izinga lokushisa kune-PTFE(polymer), inamandla aqinile uma kuqhathaniswa futhi inamandla okumelana noketshezi oluningi.Inobukhulu obuphansi (1.78 g/cc) kunamanye ama-fluoropolymer (cishe u-2.18 g/cc).Ngenxa yezinga lokushisa eliphansi lokuncibilika kunamanye ama-fluoropolymer, likwazi ukusetshenzwa kalula libe yimikhiqizo enjengamapayipi, amashubhu, izingxenye ezibunjwe ngomjovo namafilimu.Inikeza ukuqina okuhle kakhulu kobukhulu kanye ne-UV futhi ngenxa yalokho ithola ukusetshenziswa okusha endaweni yezindiza, izinzwa, i-biotechnology kanye nezimakethe zamarobhothi.
Isikhathi sokuthumela: Aug-06-2018